If one channel of the sRGB image is clipped, you can see color shifts. But are you talking about raw clipping or clipping in the developed image?
In the raw file, or in the output file?
That make me think you were probably talking about raw clipping all along. Right?
But what histogram are you talking about? The in-camera one?
What kinds of artifacts? Done right, there should be no color shifts.
Histograms aren't perfect. And you've put your finger on one of their problems. Sometimes, there is no substitute for knowing your subject and knowing your craft. Sounds like you've been there.