Just as important as the aperture etc. while shooting, which you can put into a DoF calculator, is the size of the print and the viewing distance or, combined, the angular size of the print as seen by the viewer.
As an example, take this image which was IIRC part of the launch campaign of the Canon 1Ds Mark III. All three examples are the same image at different sizes of enlargement and if you stay behind your computer at the same distance the only variable will be the 'print size'.
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The third is at 100% (one pixel of the image is displayed by one pixel of the screen) and now you can see that the ear is extremely blurry.

If you have the room, now stand up and move backward while looking at the third image and see the DoF getting deeper while the image gets smaller for you as the viewer.
If you're serious about DoF you'll have to know in advance how the image will be viewed and even what the eyesight of your viewers will be.