but we are looking at images made from microscope objectives with extremely fine detail. read the olympus imaging link a poster had provided. you want the best image quality use a larger sensor. but under most curcomstances good enough is good enough.
only under common circumstances. thats why i chose the a74 over the a7r4 or a7r5 .as i shoot low light concerts and bigger pixels produce cleaner images.
which is what we are discussing Diffraction limited also pixel bleeding, noise control. larger pixels win on all 3 . stack those 3 items 100 times and you get a less cleaner less detailed image from smaller pixels.
sounds like computational photography. i have no problem with DR. do i spent $1500 on a new microscope objective or keep what i have is my delemma atm 😁